PROGNOSIS AND THERAPEUTIC PRINCIPLE

A Review of Oral Submucousal Fibrosis, Related Factors, Prognosis and New Therapeutic Approaches

Abstract   BACKGROUNackground and AIMD & AIM: Oral Submucous Fibrosis (OSF) is an oral premalignant condition with highest premalignant potential  among oral precancerous lesions which characterized with inflammation and  progressive fibrosis of  submucosal oral tissues (cause to significant irreversible rigidity and trismus). During the years, many classification systems have been propo...

Monoamine Oxidase Inhibitors—Revisiting a Therapeutic Principle

Over more than 60 years, monoamine oxidase (MAO) inhibitors are available for therapy of central nervous diseases. Although they have shown to be efficacious specifically in the treatment of major depressive disorders and treatment-resistant depression, they became less a therapeutic choice for the physicians mostly due to severe side effects, such as liver failure and hypertensive crisis assoc...

Guided Bone Regeneration: biological principle and therapeutic applications.

The Guided Bone Regeneration (GBR) treatment concept advocates that regeneration of osseous defects is predictably attainable via the application of occlusive membranes, which mechanically exclude non-osteogenic cell populations from the surrounding soft tissues, thereby allowing osteogenic cell populations originating from the parent bone to inhabit the osseous wound. The present review discus...

Advances in Molecular Pathology: Diagnosis, Prognosis, and Therapeutic Selection

How to assess prognosis after cardiac arrest and therapeutic hypothermia

The prognosis of patients who are admitted in a comatose state following successful resuscitation after cardiac arrest remains uncertain. Although the introduction of therapeutic hypothermia (TH) and improvements in post-resuscitation care have significantly increased the number of patients who are discharged home with minimal brain damage, short-term assessment of neurological outcome remains ...